2270 piezoelectric accelerometer is usually used as a standard accelerometer to develop the measurements and transmission works, which will have a great impact on the measurement results if the installation direction is unreasonable. In order to research the relationship between its installation direction and measurement results, the working principle and the structure of it are analyzed firstly. The influence of install resonance frequency on its sensitivity and the relationship between its installation direction and install resonance frequency are discussed secondly. The experimental research is carried out at last. It shows that reasonable installation direction can ensure excellent frequency response characteristics and amplitude linearity of the accelerometer sensitivity in different applications.