In order to satisfy the needs of reference materials for water content of analytical lab, a series of certified reference materials (CRMs) have been developed, including 4 CRMs of liquid with a water content ranging from 0.139mg/g to 47.6mg/g and an expanded uncertainty ranging from 0.012mg/g to 1.1mg/g, 3 CRMs of compounds containing crystal water with a water content ranging from 50.7mg/g to 156.3mg/g and an expanded uncertainty ranging from 0.6mg/g to 1.3mg/g, and 3 CRMs of mixture with a water content ranging from 0.142mg/g to 9.90mg/g and an expanded uncertainty ranging from 0.013mg/g to 0.20mg/g. This series of CRMs are suitable for the calibration and verification of Karl Fischer coulometric titrator and volumetric titrator, and the validation of analytical method for water content, which assures the accuracy and consistency of water content results in our country.