In the development of aero-engine, many kinds of tests are needed to verify, and various kinds of parameters need to be measured to show the strict conformity. In the performance test of high pressure compressor, there are nearly all kinds of parameters to be measured, which can be used as an example to analyze the design and implementation of the main instrumentation system and calibration scheme for aero-engine. It will provide a reference for the design and implementation of the other aero-engine test rig and similar instrumentation, by summarizing the design process, which including the key points of the instrumentation system, notices in the design, and how to establish a traceability system, and clarify the calibration requirements.