The traditional method uses linear frequency modulated signal as the excitation for frequency response measurement and calibration, which can hardly balance the accuracy and efficiency because of its even power spectrum and deficient adjustable parameters. In this paper, we propose a dynamic method for frequency response calibration based on nonlinear frequency sweep. The power spectrum of the nonlinear sweep signal is inhomogeneous, so that the accuracy and efficiency of the calibrating method can be well balanced. The simulation result shows that compared with the traditional method using linear frequency sweep, our method improves the measurement accuracy within specific frequency band using the same sweeping time.